26 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Falls township | 1 | 34,161 | 34,697 | -0.28% | 1,601 | 21.33 | Township |
| Tunkhannock township | 2 | 6,795 | 7,016 | -0.83% | 176 | 38.55 | Township |
| Tunkhannock township | 3 | 3,910 | 3,969 | -0.46% | 127 | 30.81 | Township |
| Tunkhannock | 4 | 1,720 | 1,762 | -0.46% | 1,937 | 0.89 | Borough |
| Falls township | 5 | 1,664 | 1,688 | -0.48% | 81 | 20.64 | Township |
| Monroe township | 6 | 1,649 | 1,667 | -0.18% | 78 | 21.18 | Township |
| Nicholson township | 7 | 1,627 | 1,726 | -1.15% | 75 | 21.79 | Township |
| Overfield township | 8 | 1,422 | 1,424 | -0.35% | 143 | 9.92 | Township |
| Northmoreland township | 9 | 1,408 | 1,406 | -0.21% | 72 | 19.68 | Township |
| Eaton township | 10 | 1,407 | 1,434 | -0.71% | 39 | 35.99 | Township |
| Nicholson township | 11 | 1,220 | 1,262 | -0.89% | 53 | 22.92 | Township |
| Factoryville | 12 | 1,177 | 1,147 | 0.51% | 1,557 | 0.76 | Borough |
| Lemon township | 13 | 1,113 | 1,134 | -0.54% | 71 | 15.75 | Township |
| Meshoppen township | 14 | 904 | 929 | -0.77% | 58 | 15.72 | Township |
| Noxen township | 15 | 897 | 916 | -0.66% | 31 | 28.72 | Township |
| Mehoopany township | 16 | 884 | 893 | -0.45% | 51 | 17.18 | Township |
| Windham township | 17 | 727 | 736 | -0.55% | 33 | 22.23 | Township |
| Nicholson | 18 | 717 | 696 | 0.56% | 619 | 1.16 | Borough |
| Exeter township | 19 | 610 | 623 | -0.65% | 194 | 3.14 | Township |
| Noxen | 20 | 596 | 555 | -0.33% | 301 | 1.98 | CDP |
| Lake Winola | 21 | 566 | 693 | -2.08% | 367 | 1.54 | CDP |
| Braintrim township | 22 | 462 | 459 | 0.22% | 79 | 5.83 | Township |
| Laceyville | 23 | 355 | 362 | -0.28% | 1,839 | 0.19 | Borough |
| Meshoppen | 24 | 323 | 327 | -0.31% | 467 | 0.69 | Borough |
| Forkston township | 25 | 291 | 301 | -1.02% | 4 | 70.22 | Township |
| North Branch township | 26 | 229 | 236 | -0.87% | 10 | 22.38 | Township |
Falls township is the largest city in Wyoming County, with a population of 34,161.
North Branch township is the smallest city in Wyoming County.
There are 26 cities in Wyoming County, Pennsylvania.