29 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Union town | 1 | 53,257 | 55,944 | -1.05% | 1,503 | 35.44 | Town |
| Binghamton | 2 | 46,018 | 47,790 | -0.76% | 4,391 | 10.48 | City |
| Vestal town | 3 | 31,943 | 29,328 | 0.67% | 618 | 51.68 | Town |
| Johnson City | 4 | 14,616 | 15,260 | -0.87% | 3,211 | 4.55 | Village |
| Endicott | 5 | 12,927 | 13,637 | -1.09% | 4,047 | 3.19 | Village |
| Endwell | 6 | 11,921 | 11,396 | 0.27% | 3,184 | 3.74 | CDP |
| Chenango town | 7 | 10,455 | 10,936 | -0.91% | 309 | 33.83 | Town |
| Binghamton University | 8 | 6,462 | 6,162 | 0.29% | 8,338 | 0.78 | CDP |
| Fenton town | 9 | 6,121 | 6,408 | -0.89% | 187 | 32.77 | Town |
| Windsor town | 10 | 5,523 | 5,780 | -1% | 60 | 91.80 | Town |
| Kirkwood town | 11 | 5,230 | 5,479 | -0.91% | 170 | 30.71 | Town |
| Maine town | 12 | 4,945 | 5,164 | -0.88% | 109 | 45.54 | Town |
| Dickinson town | 13 | 4,940 | 5,076 | -0.2% | 1,037 | 4.76 | Town |
| Conklin town | 14 | 4,768 | 5,000 | -0.91% | 195 | 24.47 | Town |
| Colesville town | 15 | 4,654 | 4,855 | -0.89% | 59 | 78.36 | Town |
| Binghamton town | 16 | 4,412 | 4,599 | -0.76% | 175 | 25.27 | Town |
| Chenango Bridge | 17 | 3,309 | 3,155 | 0.85% | 1,351 | 2.45 | CDP |
| Triangle town | 18 | 2,688 | 2,805 | -0.85% | 71 | 37.88 | Town |
| Lisle town | 19 | 2,598 | 2,685 | -0.65% | 55 | 46.89 | Town |
| Crest View Heights | 20 | 2,322 | 1,880 | 7.1% | 1,900 | 1.22 | CDP |
| Sanford town | 21 | 2,144 | 2,231 | -0.83% | 24 | 90.08 | Town |
| Port Dickinson | 22 | 1,635 | 1,719 | -1.03% | 2,608 | 0.63 | Village |
| Nanticoke town | 23 | 1,525 | 1,573 | -0.52% | 63 | 24.27 | Town |
| Deposit | 24 | 1,399 | 1,453 | -0.78% | 1,108 | 1.26 | Village |
| Deposit town | 25 | 1,386 | 1,424 | -0.93% | 32 | 43.03 | Town |
| Whitney Point | 26 | 884 | 926 | -0.9% | 848 | 1.04 | Village |
| Windsor | 27 | 846 | 893 | -1.05% | 770 | 1.10 | Village |
| Lisle | 28 | 319 | 336 | -0.93% | 341 | 0.94 | Village |
| Glen Aubrey | 29 | 153 | 258 | -12.57% | 155 | 0.99 | CDP |
Union town is the largest city in Broome County, with a population of 53,257.
Glen Aubrey is the smallest city in Broome County.
There are 29 cities in Broome County, New York.