43 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Auburn | 1 | 25,401 | 26,855 | -1.13% | 3,048 | 8.34 | City |
| Aurora town | 2 | 13,713 | 13,848 | -0.47% | 377 | 36.39 | Town |
| Radisson | 3 | 9,044 | 6,851 | 7.14% | 2,001 | 4.52 | CDP |
| Brutus town | 4 | 4,177 | 4,308 | -0.64% | 189 | 22.11 | Town |
| Village Green | 5 | 3,711 | 3,701 | -0.32% | 3,216 | 1.15 | CDP |
| Owasco town | 6 | 3,424 | 3,550 | -0.75% | 164 | 20.88 | Town |
| Sennett town | 7 | 3,335 | 3,304 | 1.06% | 116 | 28.82 | Town |
| SUNY Oswego | 8 | 3,254 | 3,656 | -0.85% | 9,656 | 0.34 | CDP |
| Sterling town | 9 | 3,116 | 3,220 | -0.8% | 69 | 45.44 | Town |
| Moravia town | 10 | 3,009 | 3,225 | -0.82% | 104 | 28.88 | Town |
| Munsons Corners | 11 | 2,668 | 2,906 | -0.15% | 1,204 | 2.22 | CDP |
| Aurelius town | 12 | 2,503 | 2,606 | -0.83% | 83 | 30.24 | Town |
| Mentz town | 13 | 2,485 | 2,111 | 5.65% | 147 | 16.92 | Town |
| Cato town | 14 | 2,377 | 2,440 | -0.46% | 71 | 33.64 | Town |
| Fleming town | 15 | 2,367 | 2,469 | -1% | 108 | 21.82 | Town |
| Springport town | 16 | 2,130 | 2,226 | -0.93% | 99 | 21.41 | Town |
| Seneca Knolls | 17 | 2,103 | 1,759 | 0.29% | 1,660 | 1.27 | CDP |
| Ira town | 18 | 2,073 | 2,143 | -0.58% | 60 | 34.80 | Town |
| Melrose Park | 19 | 1,923 | 2,259 | -1.28% | 515 | 3.73 | CDP |
| Locke town | 20 | 1,860 | 1,877 | -0.53% | 77 | 24.30 | Town |
| Throop town | 21 | 1,784 | 1,828 | -0.39% | 96 | 18.59 | Town |
| Genoa town | 22 | 1,764 | 1,818 | -0.68% | 45 | 39.60 | Town |
| Weedsport | 23 | 1,740 | 1,809 | -0.8% | 1,783 | 0.98 | Village |
| Conquest town | 24 | 1,722 | 1,789 | -0.81% | 49 | 35.22 | Town |
| Ledyard town | 25 | 1,661 | 1,704 | 0.67% | 46 | 36.11 | Town |
| Victory town | 26 | 1,645 | 1,652 | 0.24% | 48 | 34.40 | Town |
| Scipio town | 27 | 1,494 | 1,529 | -0.33% | 41 | 36.56 | Town |
| Port Byron | 28 | 1,306 | 1,103 | 3.24% | 1,432 | 0.91 | Village |
| Moravia | 29 | 1,221 | 1,278 | -0.89% | 717 | 1.70 | Village |
| Venice town | 30 | 1,216 | 1,236 | -0.73% | 30 | 41.09 | Town |
| Montezuma town | 31 | 1,139 | 1,171 | -0.52% | 62 | 18.24 | Town |
| Niles town | 32 | 1,137 | 1,129 | 0.44% | 29 | 38.98 | Town |
| Cortland West | 33 | 1,121 | 1,313 | -1.41% | 217 | 5.17 | CDP |
| Summerhill town | 34 | 1,065 | 1,112 | -0.93% | 41 | 25.86 | Town |
| Union Springs | 35 | 1,063 | 1,105 | -0.75% | 608 | 1.75 | Village |
| Sempronius town | 36 | 883 | 845 | 0.91% | 30 | 29.34 | Town |
| Fair Haven | 37 | 759 | 789 | -0.78% | 431 | 1.76 | Village |
| Aurora | 38 | 593 | 667 | -2.47% | 645 | 0.92 | Village |
| Cato | 39 | 520 | 545 | -0.95% | 526 | 0.99 | Village |
| McLean | 40 | 486 | 226 | 7.05% | 2,095 | 0.23 | CDP |
| Cayuga | 41 | 458 | 478 | -0.87% | 507 | 0.90 | Village |
| Virgil | 42 | 290 | 574 | 7.01% | 324 | 0.89 | CDP |
| Meridian | 43 | 281 | 290 | -0.71% | 407 | 0.69 | Village |
Auburn is the largest city in Cayuga County, with a population of 25,401.
Meridian is the smallest city in Cayuga County.
There are 43 cities in Cayuga County, New York.