8 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Boonville | 1 | 7,911 | 7,588 | 0.83% | 955 | 8.28 | City |
| Pilot Grove | 2 | 688 | 663 | 0.73% | 1,634 | 0.42 | City |
| Otterville | 3 | 446 | 441 | 0.22% | 912 | 0.49 | City |
| Windsor Place | 4 | 359 | 353 | 0.28% | 400 | 0.90 | Village |
| Bunceton | 5 | 339 | 333 | 0.3% | 359 | 0.94 | City |
| Prairie Home | 6 | 263 | 262 | 0% | 678 | 0.39 | City |
| Blackwater | 7 | 181 | 173 | 1.12% | 552 | 0.33 | City |
| Wooldridge | 8 | 30 | 30 | 0% | 500 | 0.06 | Village |
Boonville is the largest city in Cooper County, with a population of 7,911.
Wooldridge is the smallest city in Cooper County.
There are 8 cities in Cooper County, Missouri.