9 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Kahoka | 1 | 1,980 | 1,967 | 0.15% | 1,247 | 1.59 | City |
| Wayland | 2 | 424 | 413 | 0.47% | 630 | 0.67 | City |
| Medill | 3 | 374 | 157 | 7.16% | 481 | 0.78 | CDP |
| Wyaconda | 4 | 206 | 213 | -0.48% | 320 | 0.64 | City |
| St. Francisville | 5 | 205 | 260 | 0.49% | 110 | 1.86 | CDP |
| Wayland township | 6 | 152 | 151 | 0% | 3 | 45.07 | Township |
| Alexandria | 7 | 106 | 105 | 0% | 281 | 0.38 | City |
| Revere | 8 | 75 | 75 | 0% | 403 | 0.19 | Town |
| Luray | 9 | 71 | 71 | 0% | 351 | 0.20 | Village |
Kahoka is the largest city in Clark County, with a population of 1,980.
Luray is the smallest city in Clark County.
There are 9 cities in Clark County, Missouri.