6 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Iuka | 1 | 3,033 | 3,142 | -0.72% | 313 | 9.69 | City |
| Belmont | 2 | 1,785 | 1,859 | -0.83% | 377 | 4.73 | Town |
| Burnsville | 3 | 835 | 860 | -0.6% | 175 | 4.77 | Town |
| Tishomingo | 4 | 356 | 373 | -0.84% | 417 | 0.85 | Town |
| Dennis | 5 | 26 | 64 | 8.33% | 19 | 1.36 | CDP |
| Childers Hill | 6 | 25 | 155 | 8.7% | 21 | 1.21 | CDP |
Iuka is the largest city in Tishomingo County, with a population of 3,033.
Childers Hill is the smallest city in Tishomingo County.
There are 6 cities in Tishomingo County, Mississippi.