12 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Pascagoula | 1 | 21,324 | 21,969 | -0.6% | 1,387 | 15.38 | City |
| Ocean Springs | 2 | 19,375 | 18,429 | 0.99% | 1,677 | 11.55 | City |
| Gautier | 3 | 19,025 | 19,014 | 0.01% | 629 | 30.26 | City |
| Moss Point | 4 | 11,733 | 12,125 | -0.66% | 487 | 24.11 | City |
| Gulf Hills | 5 | 9,023 | 8,824 | 1.4% | 1,167 | 7.74 | CDP |
| Gulf Park Estates | 6 | 7,276 | 6,238 | 1.44% | 2,740 | 2.65 | CDP |
| Vancleave | 7 | 5,037 | 4,934 | -1.12% | 117 | 43.14 | CDP |
| Escatawpa | 8 | 3,118 | 2,958 | -1.27% | 467 | 6.68 | CDP |
| Wade | 9 | 1,418 | 1,829 | 1.65% | 230 | 6.17 | CDP |
| Hurley | 10 | 1,351 | 1,279 | -0.95% | 263 | 5.13 | CDP |
| Big Point | 11 | 995 | 620 | 2.68% | 339 | 2.94 | CDP |
| Helena | 12 | 569 | 794 | -6.72% | 136 | 4.19 | CDP |
Pascagoula is the largest city in Jackson County, with a population of 21,324.
Helena is the smallest city in Jackson County.
There are 12 cities in Jackson County, Mississippi.