3 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Picayune | 1 | 11,856 | 11,870 | -0.03% | 657 | 18.04 | City |
| Poplarville | 2 | 2,813 | 2,825 | -0.07% | 520 | 5.41 | City |
| Nicholson | 3 | 2,013 | 2,477 | -3.45% | 333 | 6.04 | CDP |
Picayune is the largest city in Pearl River County, with a population of 11,856.
Nicholson is the smallest city in Pearl River County.
There are 3 cities in Pearl River County, Mississippi.