8 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Clarksdale | 1 | 13,237 | 14,769 | -2.26% | 704 | 18.79 | City |
| Jonestown | 2 | 866 | 956 | -2.04% | 2,238 | 0.39 | Town |
| Friars Point | 3 | 805 | 892 | -2.07% | 732 | 1.10 | Town |
| Farrell | 4 | 277 | 292 | 1.47% | 213 | 1.30 | CDP |
| Rena Lara | 5 | 271 | 181 | 7.11% | 118 | 2.29 | CDP |
| Lyon | 6 | 256 | 291 | -2.66% | 531 | 0.48 | Town |
| Coahoma | 7 | 210 | 232 | -1.87% | 1,071 | 0.20 | Town |
| Lula | 8 | 182 | 201 | -2.15% | 436 | 0.42 | Town |
Clarksdale is the largest city in Coahoma County, with a population of 13,237.
Lula is the smallest city in Coahoma County.
There are 8 cities in Coahoma County, Mississippi.