21 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Laredo | 1 | 259,010 | 255,489 | 0.27% | 2,425 | 106.82 | City |
| Rio Bravo | 2 | 4,324 | 4,559 | -1.08% | 6,652 | 0.65 | City |
| El Cenizo | 3 | 2,366 | 2,531 | -1.38% | 4,594 | 0.52 | City |
| Pueblo Nuevo | 4 | 581 | 721 | 0.69% | 998 | 0.58 | CDP |
| Ranchos Penitas West | 5 | 571 | 759 | 0% | 276 | 2.07 | CDP |
| Bruni | 6 | 464 | 383 | 1.31% | 353 | 1.31 | CDP |
| Ranchitos Las Lomas | 7 | 395 | 478 | 2.33% | 109 | 3.64 | CDP |
| Ranchitos East | 8 | 338 | 393 | 2.42% | 5,541 | 0.06 | CDP |
| San Carlos II | 9 | 275 | 347 | 0.36% | 3,873 | 0.07 | CDP |
| San Carlos I | 10 | 212 | 309 | -3.2% | 1,594 | 0.13 | CDP |
| Tanquecitos South Acres | 11 | 212 | 243 | -0.47% | 444 | 0.48 | CDP |
| La Presa | 12 | 195 | 249 | -4.41% | 392 | 0.50 | CDP |
| Mirando City | 13 | 155 | 366 | -8.82% | 487 | 0.32 | CDP |
| Oilton | 14 | 74 | 170 | -20.43% | 52 | 1.42 | CDP |
| Los Altos | 15 | 62 | 141 | -8.82% | 1,632 | 0.04 | CDP |
| Los Veteranos I | 16 | 49 | 48 | 6.52% | 124 | 0.39 | CDP |
| La Moca Ranch | 17 | 43 | 46 | 7.5% | 3 | 15.05 | CDP |
| Sunset Acres | 18 | 31 | 22 | 6.9% | 1,824 | 0.02 | CDP |
| Los Arcos | 19 | 20 | 38 | -25.93% | 97 | 0.21 | CDP |
| Colorado Acres | 20 | 18 | 57 | -51.35% | 6 | 2.94 | CDP |
| Los Veteranos II | 21 | 16 | 31 | 6.67% | 101 | 0.16 | CDP |
Laredo is the largest city in Webb County, with a population of 259,010.
Los Veteranos II is the smallest city in Webb County.
There are 21 cities in Webb County, Texas.