4 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Woodville | 1 | 2,402 | 2,406 | -0.04% | 764 | 3.15 | Town |
| Warren | 2 | 725 | 973 | -0.28% | 172 | 4.22 | CDP |
| Colmesneil | 3 | 551 | 538 | 0.55% | 275 | 2 | City |
| Chester | 4 | 274 | 271 | 0.37% | 174 | 1.57 | Town |
Woodville is the largest city in Tyler County, with a population of 2,402.
Chester is the smallest city in Tyler County.
There are 4 cities in Tyler County, Texas.