10 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Portland | 1 | 20,529 | 20,409 | 0.12% | 1,687 | 12.17 | City |
| Ingleside | 2 | 10,499 | 9,618 | 1.7% | 621 | 16.90 | City |
| Aransas Pass | 3 | 9,103 | 8,653 | 1% | 574 | 15.85 | City |
| Sinton | 4 | 5,594 | 5,486 | 0.39% | 1,623 | 3.45 | City |
| Mathis | 5 | 4,261 | 4,320 | -0.28% | 1,285 | 3.32 | City |
| Taft | 6 | 2,988 | 2,803 | 1.25% | 1,790 | 1.67 | City |
| Odem | 7 | 2,328 | 2,263 | 0.56% | 1,827 | 1.27 | City |
| Gregory | 8 | 1,715 | 1,737 | -0.23% | 1,125 | 1.52 | City |
| Ingleside Bay | 9 | 597 | 609 | -0.33% | 2,045 | 0.29 | City |
| Edroy | 10 | 420 | 318 | 1.45% | 190 | 2.21 | CDP |
Portland is the largest city in San Patricio County, with a population of 20,529.
Edroy is the smallest city in San Patricio County.
There are 10 cities in San Patricio County, Texas.