10 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Jacksonville | 1 | 14,680 | 14,030 | 0.89% | 969 | 15.15 | City |
| Rusk | 2 | 5,409 | 5,291 | 0.45% | 748 | 7.23 | City |
| Shadybrook | 3 | 2,402 | 2,655 | 1.22% | 311 | 7.72 | CDP |
| Alto | 4 | 1,071 | 1,028 | 0.85% | 628 | 1.71 | Town |
| Emerald Bay | 5 | 950 | 1,023 | -0.63% | 1,234 | 0.77 | CDP |
| New Summerfield | 6 | 916 | 846 | 1.55% | 195 | 4.70 | City |
| Wells | 7 | 894 | 856 | 0.9% | 467 | 1.92 | Town |
| Gallatin | 8 | 352 | 322 | 1.73% | 76 | 4.60 | City |
| Reklaw | 9 | 350 | 335 | 0.86% | 119 | 2.94 | City |
| Cuney | 10 | 116 | 113 | 0.87% | 71 | 1.64 | Town |
Jacksonville is the largest city in Cherokee County, with a population of 14,680.
Cuney is the smallest city in Cherokee County.
There are 10 cities in Cherokee County, Texas.