8 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Corydon | 1 | 1,547 | 1,522 | 0.32% | 1,132 | 1.37 | City |
| Seymour | 2 | 641 | 636 | 0.16% | 268 | 2.39 | City |
| Humeston | 3 | 472 | 466 | 0.21% | 756 | 0.62 | City |
| Allerton | 4 | 432 | 431 | 0% | 364 | 1.19 | City |
| Lineville | 5 | 192 | 192 | 0% | 213 | 0.90 | City |
| Promise City | 6 | 91 | 90 | 0% | 495 | 0.18 | City |
| Clio | 7 | 67 | 66 | 0% | 90 | 0.75 | City |
| Millerton | 8 | 43 | 43 | 0% | 147 | 0.29 | City |
Corydon is the largest city in Wayne County, with a population of 1,547.
Millerton is the smallest city in Wayne County.
There are 8 cities in Wayne County, Iowa.