8 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Jackson | 1 | 4,394 | 4,721 | -1.46% | 281 | 15.64 | City |
| Thomasville | 2 | 3,501 | 3,705 | -1.16% | 311 | 11.26 | City |
| Grove Hill | 3 | 1,695 | 1,812 | -1.34% | 223 | 7.59 | Town |
| Coffeeville | 4 | 244 | 258 | -1.21% | 54 | 4.52 | Town |
| Whatley | 5 | 231 | 279 | 2.21% | 179 | 1.29 | CDP |
| Fulton | 6 | 211 | 223 | -0.94% | 86 | 2.45 | Town |
| Carlton | 7 | 71 | 57 | 7.58% | 16 | 4.52 | CDP |
| Putnam | 8 | 28 | 54 | -28.21% | 3 | 9.48 | CDP |
Jackson is the largest city in Clarke County, with a population of 4,394.
Putnam is the smallest city in Clarke County.
There are 8 cities in Clarke County, Alabama.