21 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Harrisburg township | 1 | 9,493 | 10,007 | -0.84% | 260 | 36.47 | Township |
| Harrisburg | 2 | 7,713 | 8,197 | -1.24% | 1,167 | 6.61 | City |
| East Eldorado township | 3 | 5,153 | 5,416 | -0.77% | 141 | 36.47 | Township |
| Eldorado | 4 | 3,521 | 3,735 | -1.21% | 1,407 | 2.50 | City |
| Carrier Mills township | 5 | 2,206 | 2,316 | -0.68% | 60 | 37.01 | Township |
| Carrier Mills | 6 | 1,565 | 1,665 | -1.26% | 1,296 | 1.21 | Village |
| Independence township | 7 | 1,127 | 1,183 | -0.79% | 31 | 36.84 | Township |
| Raleigh township | 8 | 1,053 | 1,105 | -0.75% | 29 | 36.02 | Township |
| Galatia township | 9 | 1,047 | 1,100 | -0.76% | 56 | 18.61 | Township |
| Brushy township | 10 | 941 | 989 | -0.74% | 28 | 33.82 | Township |
| Galatia | 11 | 773 | 823 | -1.28% | 396 | 1.95 | Village |
| Stonefort township | 12 | 363 | 373 | -0.27% | 21 | 17.59 | Township |
| Mountain township | 13 | 344 | 365 | -0.86% | 8 | 42 | Township |
| Tate township | 14 | 274 | 290 | -0.72% | 15 | 18.13 | Township |
| Raleigh | 15 | 271 | 288 | -1.09% | 137 | 1.98 | Village |
| Long Branch township | 16 | 237 | 249 | -0.84% | 13 | 18.25 | Township |
| Stonefort | 17 | 218 | 223 | -0.46% | 150 | 1.45 | Village |
| Cottage township | 18 | 215 | 230 | -1.38% | 7 | 30.60 | Township |
| Eldorado township | 19 | 132 | 135 | -0.75% | 4 | 36.47 | Township |
| Rector township | 20 | 62 | 67 | -1.59% | 3 | 18.19 | Township |
| Muddy | 21 | 54 | 58 | -1.82% | 178 | 0.30 | Village |
Harrisburg township is the largest city in Saline County, with a population of 9,493.
Muddy is the smallest city in Saline County.
There are 21 cities in Saline County, Illinois.