City | Rank | County | 2024 Pop. |
|---|---|---|---|
| Condon | 1 | Gilliam County | 718 |
| Arlington | 2 | Gilliam County | 641 |
| Fossil | 3 | Wheeler County | 443 |
| Wasco | 4 | Sherman County | 443 |
| Moro | 5 | Sherman County | 384 |
| Rufus | 6 | Sherman County | 281 |
| Grass Valley | 7 | Sherman County | 164 |
| Mitchell | 8 | Wheeler County | 136 |
| Antelope | 9 | Wasco County | 39 |
| Shaniko | 10 | Wasco County | 30 |