45 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Redfield | 1 | 2,077 | 2,211 | -1.28% | 1,077 | 1.93 | City |
| Redfield township | 2 | 380 | 387 | -0.26% | 11 | 34.92 | Township |
| Lincoln township | 3 | 341 | 342 | 0.29% | 10 | 35.32 | Township |
| Capitola township | 4 | 270 | 270 | 0.37% | 8 | 35.98 | Township |
| Glendale Colony | 5 | 254 | 190 | 7.17% | 530 | 0.48 | CDP |
| Tulare | 6 | 202 | 209 | -0.49% | 789 | 0.26 | Town |
| Mellette | 7 | 193 | 198 | -0.52% | 754 | 0.26 | City |
| Doland | 8 | 185 | 195 | -1.07% | 315 | 0.59 | City |
| Northville township | 9 | 150 | 156 | -0.66% | 2 | 99.05 | Township |
| Conde | 10 | 137 | 144 | -0.72% | 243 | 0.56 | City |
| Northville | 11 | 134 | 139 | -0.74% | 356 | 0.38 | Town |
| Frankfort | 12 | 127 | 134 | -0.78% | 161 | 0.79 | City |
| Mellette township | 13 | 111 | 114 | 0% | 1 | 75.48 | Township |
| Prairie Center township | 14 | 108 | 117 | -1.82% | 3 | 35.98 | Township |
| Ashton | 15 | 104 | 108 | -0.95% | 237 | 0.44 | City |
| Lake township | 16 | 95 | 100 | -1.04% | 3 | 33.25 | Township |
| Brentford | 17 | 82 | 86 | -1.2% | 503 | 0.16 | Town |
| Belle Plaine township | 18 | 77 | 82 | -1.28% | 2 | 36.08 | Township |
| Crandon township | 19 | 76 | 75 | 1.33% | 2 | 35.81 | Township |
| Belmont township | 20 | 72 | 68 | 2.86% | 2 | 35.94 | Township |
| Three Rivers township | 21 | 60 | 65 | -1.64% | 2 | 35.98 | Township |
| Exline township | 22 | 58 | 63 | -1.69% | 2 | 36.71 | Township |
| La Prairie township | 23 | 55 | 62 | -3.51% | 1 | 49.85 | Township |
| Athol township | 24 | 54 | 55 | 0% | 1 | 47.81 | Township |
| Turton | 25 | 53 | 55 | 0% | 144 | 0.37 | Town |
| Groveland township | 26 | 52 | 56 | -1.89% | 1 | 36.01 | Township |
| Lodi township | 27 | 52 | 56 | -1.89% | 1 | 36.65 | Township |
| Antelope township | 28 | 51 | 55 | -1.92% | 1 | 35.93 | Township |
| Tulare township | 29 | 50 | 48 | 2.04% | 1 | 33.81 | Township |
| Garfield township | 30 | 49 | 53 | -2% | 1 | 35.89 | Township |
| Union township | 31 | 49 | 47 | 2.08% | 1 | 36.01 | Township |
| Harmony township | 32 | 48 | 52 | -2.04% | 1 | 36.10 | Township |
| Frankfort township | 33 | 47 | 45 | 2.17% | 1 | 35.10 | Township |
| Clifton township | 34 | 40 | 38 | 2.56% | 1 | 48.22 | Township |
| Olean township | 35 | 38 | 42 | -2.56% | 1 | 36.09 | Township |
| Tetonka township | 36 | 38 | 42 | -2.56% | 1 | 58.77 | Township |
| Great Bend township | 37 | 37 | 41 | -2.63% | 1 | 35.99 | Township |
| Cornwall township | 38 | 36 | 38 | -2.7% | 1 | 35.52 | Township |
| Conde township | 39 | 26 | 27 | 0% | 1 | 35.35 | Township |
| Spring township | 40 | 26 | 27 | 0% | 1 | 35.78 | Township |
| Benton township | 41 | 25 | 26 | 0% | 1 | 36.09 | Township |
| Turton township | 42 | 25 | 26 | 0% | 1 | 35.77 | Township |
| Richfield township | 43 | 21 | 22 | 0% | 1 | 35.67 | Township |
| Beotia township | 44 | 19 | 22 | -5% | 1 | 35.54 | Township |
| Sumner township | 45 | 11 | 14 | -8.33% | 0.00 | 36.09 | Township |
Redfield is the largest city in Spink County, with a population of 2,077.
Sumner township is the smallest city in Spink County.
There are 45 cities in Spink County, South Dakota.