11 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Eureka | 1 | 750 | 807 | -1.45% | 804 | 0.93 | City |
| Leola | 2 | 404 | 433 | -1.46% | 544 | 0.74 | City |
| Weber township | 3 | 230 | 243 | -1.71% | 6 | 36.51 | Township |
| Eureka township | 4 | 190 | 176 | 1.06% | 5 | 36.27 | Township |
| Leola township | 5 | 68 | 60 | 4.62% | 2 | 33.20 | Township |
| Eureka township | 6 | 41 | 41 | 0% | 1 | 34.31 | Township |
| Carl township | 7 | 34 | 31 | 3.03% | 1 | 35.28 | Township |
| Wachter township | 8 | 30 | 31 | 0% | 1 | 34.47 | Township |
| Long Lake | 9 | 27 | 27 | 0% | 97 | 0.28 | Town |
| Hoffman township | 10 | 17 | 20 | -5.56% | 0.00 | 35.30 | Township |
| Wacker township | 11 | 14 | 17 | -6.67% | 0.00 | 34.69 | Township |
Eureka is the largest city in McPherson County, with a population of 750.
Wacker township is the smallest city in McPherson County.
There are 11 cities in McPherson County, South Dakota.