12 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Shawnee | 1 | 32,125 | 31,319 | 0.5% | 832 | 38.61 | City |
| Tecumseh | 2 | 6,353 | 6,308 | 0.14% | 423 | 15.02 | City |
| McLoud | 3 | 4,571 | 4,363 | 0.93% | 254 | 18.02 | City |
| Bethel Acres | 4 | 3,300 | 3,045 | 1.57% | 117 | 28.27 | Town |
| Maud | 5 | 877 | 866 | 0.23% | 836 | 1.05 | City |
| Earlsboro | 6 | 616 | 595 | 0.65% | 66 | 9.29 | Town |
| Johnson | 7 | 469 | 458 | 0.43% | 105 | 4.47 | Town |
| Asher | 8 | 376 | 370 | 0.27% | 490 | 0.77 | Town |
| Wanette | 9 | 282 | 277 | 0.36% | 695 | 0.41 | Town |
| St. Louis | 10 | 129 | 128 | 0% | 14 | 9.44 | Town |
| Brooksville | 11 | 72 | 72 | 0% | 24 | 2.98 | Town |
| Macomb | 12 | 24 | 24 | 0% | 270 | 0.09 | Town |
Shawnee is the largest city in Pottawatomie County, with a population of 32,125.
Macomb is the smallest city in Pottawatomie County.
There are 12 cities in Pottawatomie County, Oklahoma.