9 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Pond Creek | 1 | 875 | 892 | -0.34% | 1,031 | 0.85 | City |
| Medford | 2 | 866 | 913 | -1.03% | 714 | 1.21 | City |
| Wakita | 3 | 299 | 311 | -0.66% | 961 | 0.31 | Town |
| Lamont | 4 | 280 | 299 | -1.41% | 826 | 0.34 | Town |
| Nash | 5 | 184 | 191 | -0.54% | 554 | 0.33 | Town |
| Manchester | 6 | 85 | 89 | -1.16% | 351 | 0.24 | Town |
| Deer Creek | 7 | 72 | 76 | -1.37% | 507 | 0.14 | Town |
| Renfrow | 8 | 19 | 19 | 0% | 198 | 0.10 | Town |
| Jefferson | 9 | 11 | 11 | 0% | 40 | 0.27 | Town |
Pond Creek is the largest city in Grant County, with a population of 875.
Jefferson is the smallest city in Grant County.
There are 9 cities in Grant County, Oklahoma.