6 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Keysville | 1 | 782 | 812 | -0.76% | 665 | 1.18 | Town |
| Drakes Branch | 2 | 510 | 530 | -0.78% | 123 | 4.14 | Town |
| Charlotte Court House | 3 | 491 | 508 | -0.61% | 124 | 3.96 | Town |
| Fairview | 4 | 282 | 145 | 0.71% | 265 | 1.06 | CDP |
| Phenix | 5 | 226 | 231 | -0.44% | 196 | 1.15 | Town |
| Thynedale | 6 | 17 | 49 | -41.38% | 23 | 0.74 | CDP |
Keysville is the largest city in Charlotte County, with a population of 782.
Thynedale is the smallest city in Charlotte County.
There are 6 cities in Charlotte County, Virginia.