Zip Code | City | Population |
|---|---|---|
| 16125 | Greenville | 17,610 |
| 16148 | Hermitage | 16,710 |
| 16127 | Grove City | 15,350 |
| 16146 | Sharon | 13,169 |
| 16137 | Mercer | 12,710 |
| 16150 | Sharpsville | 7,045 |
| 16142 | New Wilmington | 5,391 |
| 16159 | West Middlesex | 4,616 |
| 16121 | Farrell | 4,309 |
| 16145 | Sandy Lake | 2,693 |
| 16153 | Stoneboro | 2,266 |
| 16154 | Transfer | 1,987 |
| 16130 | Hadley | 1,982 |
| 16124 | Fredonia | 1,704 |
| 16133 | Jackson Center | 1,570 |
| 16114 | Clarks Mills | 561 |
| 16161 | Wheatland | 506 |
| 16311 | Carlton | 438 |
| 16113 | Clark | 349 |
| 16151 | Sheakleyville | 58 |