Note: As defined by the US Census Bureau, a city's official boundaries often extend miles beyond the city itself and may even cross county lines. As such, several thousand US cities officially exist in two or more counties (and therefore appear on multiple counties' lists of cities.)
City | Rank | 2024 Pop. | 2020 Pop. | Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Spartanburg | 1 | 39,184 | 38,608 | 0.37% | 1,935 | 20.3 | City |
| Boiling Springs | 2 | 11,686 | 9,953 | 2.16% | 1,709 | 6.8 | CDP |
| Valley Falls | 3 | 7,238 | 7,269 | 0.93% | 1,395 | 5.2 | CDP |
| Lyman | 4 | 6,876 | 6,206 | 2.49% | 1,038 | 6.6 | Town |
| Woodruff | 5 | 4,683 | 4,227 | 2.5% | 923 | 5.1 | City |
| Duncan | 6 | 4,553 | 4,065 | 2.75% | 726 | 6.3 | Town |
| Whitney | 7 | 4,356 | 3,999 | 7.69% | 1,428 | 3.1 | CDP |
| Saxon | 8 | 4,296 | 3,727 | 1.49% | 1,804 | 2.4 | CDP |
| Roebuck | 9 | 4,110 | 2,768 | 3.45% | 958 | 4.3 | CDP |
| Southern Shops | 10 | 3,871 | 3,965 | 0.21% | 1,086 | 3.6 | CDP |
| Hilltop | 11 | 3,795 | 3,483 | 7.69% | 2,079 | 1.8 | CDP |
| Wellford | 12 | 3,718 | 3,354 | 2.51% | 812 | 4.6 | City |
| Inman | 13 | 3,329 | 3,007 | 2.46% | 1,898 | 1.8 | City |
| Arkwright | 14 | 3,020 | 2,493 | 7.66% | 1,169 | 2.6 | CDP |
| Arcadia | 15 | 2,881 | 2,991 | 0.59% | 1,470 | 2.0 | CDP |
| Landrum | 16 | 2,765 | 2,491 | 2.52% | 1,045 | 2.6 | City |
| Pacolet | 17 | 2,540 | 2,288 | 2.54% | 440 | 5.8 | Town |
| Ben Avon | 18 | 2,521 | 2,189 | 7.69% | 1,509 | 1.7 | CDP |
| Cowpens | 19 | 2,244 | 2,027 | 2.47% | 978 | 2.3 | Town |
| Mayo | 20 | 1,980 | 1,770 | 1.38% | 651 | 3.0 | CDP |
| Camp Croft | 21 | 1,975 | 1,991 | 7.69% | 746 | 2.6 | CDP |
| Reidville | 22 | 1,831 | 1,645 | 2.58% | 1,040 | 1.8 | Town |
| Fairforest | 23 | 1,615 | 1,484 | -0.31% | 772 | 2.1 | CDP |
| Drayton | 24 | 1,180 | 1,097 | 7.76% | 842 | 1.4 | CDP |
| Clifton | 25 | 1,032 | 691 | 3.51% | 962 | 1.1 | CDP |
| Inman Mills | 26 | 940 | 801 | -0.84% | 871 | 1.1 | CDP |
| Chesnee | 27 | 927 | 838 | 2.43% | 866 | 1.1 | City |
| Campobello | 28 | 757 | 681 | 2.57% | 272 | 2.8 | Town |
| Startex | 29 | 502 | 556 | -4.92% | 453 | 1.1 | CDP |
| Enoree | 30 | 404 | 560 | -4.26% | 261 | 1.5 | CDP |
| Pauline | 31 | 267 | 204 | 7.66% | 187 | 1.4 | CDP |
| Glendale | 32 | 245 | 312 | -2% | 1,156 | 0.2 | CDP |
| Glenn Springs | 33 | 218 | 231 | 7.39% | 98 | 2.2 | CDP |
| Converse | 34 | 180 | 545 | -14.29% | 261 | 0.7 | CDP |
| Fingerville | 35 | 93 | 31 | -3.13% | 381 | 0.2 | CDP |
| Gramling | 36 | 92 | 97 | 6.98% | 92 | 1.0 | CDP |
| Cross Anchor | 37 | 8 | 70 | -52.94% | 10 | 0.8 | CDP |
Note: City markers shown outside the county boundary mean that a part of the city extends into this county, but is primarily located in an adjacent county.
Spartanburg is the largest city in Spartanburg County.
Cross Anchor is the smallest city in Spartanburg County.
There are 37 cities in Spartanburg County, South Carolina.