Note: As defined by the US Census Bureau, a city's official boundaries often extend miles beyond the city itself and may even cross county lines. As such, several thousand US cities officially exist in two or more counties (and therefore appear on multiple counties' lists of cities.)
City | Rank | 2024 Pop. | 2020 Pop. | Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Anderson | 1 | 30,148 | 29,476 | 0.56% | 1,883 | 16.0 | City |
| Berea | 2 | 16,499 | 15,104 | 0.97% | 2,143 | 7.7 | CDP |
| Powdersville | 3 | 12,458 | 9,436 | 7.69% | 906 | 13.8 | CDP |
| Homeland Park | 4 | 7,644 | 6,570 | 1.29% | 1,623 | 4.7 | CDP |
| Centerville | 5 | 7,322 | 6,816 | 0.71% | 1,240 | 5.9 | CDP |
| Clemson University | 6 | 7,253 | 5,329 | 7.69% | 3,426 | 2.1 | CDP |
| Welcome | 7 | 7,234 | 7,743 | 0.57% | 1,568 | 4.6 | CDP |
| Belton | 8 | 4,567 | 4,343 | 1.24% | 1,196 | 3.8 | City |
| Williamston | 9 | 4,274 | 4,054 | 1.3% | 1,159 | 3.7 | Town |
| Northlake | 10 | 4,030 | 3,684 | 0.52% | 974 | 4.1 | CDP |
| Honea Path | 11 | 3,900 | 3,690 | 1.35% | 1,110 | 3.5 | Town |
| Pendleton | 12 | 3,709 | 3,499 | 1.42% | 756 | 4.9 | Town |
| Golden Grove | 13 | 3,418 | 3,449 | 2.03% | 592 | 5.8 | CDP |
| Pelzer | 14 | 1,422 | 1,345 | 1.35% | 1,556 | 0.9 | Town |
| Iva | 15 | 1,188 | 1,130 | 1.19% | 1,160 | 1.0 | Town |
| La France | 16 | 1,156 | 856 | 7.63% | 892 | 1.3 | CDP |
| Cateechee | 17 | 1,135 | 738 | 7.69% | 2,221 | 0.5 | CDP |
| West Pelzer | 18 | 1,020 | 964 | 1.39% | 1,694 | 0.6 | Town |
| Sandy Springs | 19 | 1,018 | 974 | 7.61% | 354 | 2.9 | CDP |
| Chickasaw Point | 20 | 704 | 532 | 7.81% | 322 | 2.2 | CDP |
| South Union | 21 | 447 | 332 | 7.71% | 172 | 2.6 | CDP |
| Starr | 22 | 174 | 164 | 1.16% | 116 | 1.5 | Town |
| Ware Place | 23 | 74 | 116 | -12.94% | 81 | 0.9 | CDP |
Note: City markers shown outside the county boundary mean that a part of the city extends into this county, but is primarily located in an adjacent county.
Anderson is the largest city in Anderson County.
Ware Place is the smallest city in Anderson County.
There are 23 cities in Anderson County, South Carolina.