Mississippi County, Missouri Cities (2024)

Note: As defined by the US Census Bureau, a city's official boundaries often extend miles beyond the city itself and may even cross county lines. As such, several thousand US cities officially exist in two or more counties (and therefore appear on multiple counties' lists of cities.)

City
Rank
2024 Pop.
2020 Pop.
Change
Density (/mi²)
Area (mi²)
Type
Charleston14,4404,611-0.96%9264.8City
East Prairie22,8472,937-0.8%2,2781.3City
Miner3896910-0.44%1944.6City
Bertrand4696716-0.71%8450.8City
Wyatt5211221-1.4%1801.2City
Anniston6177180-0.56%4530.4Town
Whiting71771347.27%6780.3CDP
Diehlstadt8156159-0.64%2,1080.1Village
Wilson City97477-1.33%9870.1Village

Note: City markers shown outside the county boundary mean that a part of the city extends into this county, but is primarily located in an adjacent county.

What is the largest city in Mississippi County, Missouri?

Charleston is the largest city in Mississippi County.

What is the smallest city in Mississippi County, Missouri?

Wilson City is the smallest city in Mississippi County.

How many cities are in Mississippi County?

There are 9 cities in Mississippi County, Missouri.

Frequently Asked Questions