Note: As defined by the US Census Bureau, a city's official boundaries often extend miles beyond the city itself and may even cross county lines. As such, several thousand US cities officially exist in two or more counties (and therefore appear on multiple counties' lists of cities.)
City | Rank | 2024 Pop. | 2020 Pop. | Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Granite City | 1 | 26,705 | 27,516 | -0.75% | 1,404 | 19.0 | City |
| Edwardsville | 2 | 26,663 | 26,803 | -0.13% | 1,334 | 20.0 | City |
| Alton | 3 | 24,805 | 25,608 | -0.8% | 1,583 | 15.7 | City |
| Collinsville | 4 | 23,596 | 24,327 | -0.77% | 1,548 | 15.2 | City |
| Godfrey | 5 | 17,526 | 17,808 | -0.4% | 510 | 34.4 | Village |
| Glen Carbon | 6 | 13,870 | 13,862 | 0.01% | 1,345 | 10.3 | Village |
| Troy | 7 | 11,295 | 10,950 | 0.77% | 1,984 | 5.7 | City |
| Wood River | 8 | 10,215 | 10,434 | -0.54% | 1,464 | 7.0 | City |
| Highland | 9 | 9,935 | 10,038 | -0.26% | 1,420 | 7.0 | City |
| Bethalto | 10 | 9,125 | 9,305 | -0.49% | 1,202 | 7.6 | Village |
| Maryville | 11 | 8,335 | 8,257 | 0.23% | 1,444 | 5.8 | Village |
| Pontoon Beach | 12 | 5,786 | 5,858 | -0.31% | 581 | 10.0 | Village |
| East Alton | 13 | 5,595 | 5,771 | -0.78% | 1,052 | 5.3 | Village |
| Rosewood Heights | 14 | 3,900 | 3,990 | -0.26% | 2,334 | 1.7 | CDP |
| Holiday Shores | 15 | 3,352 | 3,080 | 0.99% | 2,119 | 1.6 | CDP |
| Madison | 16 | 3,041 | 3,137 | -0.78% | 215 | 14.1 | City |
| Washington Park | 17 | 2,466 | 2,573 | -1.08% | 966 | 2.6 | Village |
| Fairmont City | 18 | 2,147 | 2,255 | -1.24% | 346 | 6.2 | Village |
| South Roxana | 19 | 1,842 | 1,888 | -0.65% | 854 | 2.2 | Village |
| Venice | 20 | 1,446 | 1,490 | -0.76% | 782 | 1.8 | City |
| Roxana | 21 | 1,401 | 1,448 | -0.85% | 197 | 7.1 | Village |
| St. Jacob | 22 | 1,367 | 1,374 | -0.15% | 1,614 | 0.8 | Village |
| Hartford | 23 | 1,147 | 1,186 | -0.86% | 221 | 5.2 | Village |
| Worden | 24 | 1,062 | 1,094 | -0.75% | 1,489 | 0.7 | Village |
| Marine | 25 | 951 | 909 | 1.06% | 1,349 | 0.7 | Village |
| Hamel | 26 | 916 | 924 | -0.22% | 770 | 1.2 | Village |
| Mitchell | 27 | 873 | 1,233 | -3.85% | 1,562 | 0.6 | CDP |
| Livingston | 28 | 739 | 763 | -0.8% | 711 | 1.0 | Village |
| Alhambra | 29 | 604 | 620 | -0.66% | 799 | 0.8 | Village |
| Moro | 30 | 490 | 362 | 7.69% | 2,237 | 0.2 | CDP |
| New Douglas | 31 | 335 | 346 | -0.89% | 320 | 1.0 | Village |
| Sauget | 32 | 130 | 138 | -1.52% | 28 | 4.6 | Village |
Note: City markers shown outside the county boundary mean that a part of the city extends into this county, but is primarily located in an adjacent county.
Granite City is the largest city in Madison County.
Sauget is the smallest city in Madison County.
There are 32 cities in Madison County, Illinois.