34 zips
| Zip Code | City | Population ↓ |
|---|---|---|
| 34135 | Bonita Springs | 45,781 |
| 33914 | Cape Coral | 43,289 |
| 33905 | Fort Myers | 39,247 |
| 33908 | Fort Myers | 38,844 |
| 33909 | Cape Coral | 36,172 |
| 33990 | Cape Coral | 34,275 |
| 33904 | Cape Coral | 32,345 |
| 33993 | Cape Coral | 30,572 |
| 33917 | North Fort Myers | 30,512 |
| 33928 | Estero | 29,948 |
| 33971 | Lehigh Acres | 28,712 |
| 33919 | Fort Myers | 28,483 |
| 33967 | Fort Myers | 27,887 |
| 33913 | Fort Myers | 27,056 |
| 33916 | Fort Myers | 26,153 |
| 33907 | Fort Myers | 25,828 |
| 33991 | Cape Coral | 24,993 |
| 33901 | Fort Myers | 24,284 |
| 33903 | North Fort Myers | 22,430 |
| 33912 | Fort Myers | 19,370 |
| 33974 | Lehigh Acres | 19,218 |
| 33976 | Lehigh Acres | 17,874 |
| 34134 | Bonita Springs | 15,859 |
| 33972 | Lehigh Acres | 15,218 |
| 33973 | Lehigh Acres | 14,585 |
| 33966 | Fort Myers | 11,236 |
| 33931 | Fort Myers Beach | 9,150 |
| 33920 | Alva | 7,250 |
| 33957 | Sanibel | 6,420 |
| 33922 | Bokeelia | 4,235 |
| 33965 | Fort Myers | 3,793 |
| 33956 | Saint James City | 3,494 |
| 33921 | Boca Grande | 726 |
| 33924 | Captiva | 161 |
The data shown reflect ZCTAs from the US Census. As of 2024, there are 34 ZCTAs in Lee County, Florida (US Census).