14 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Metlakatla | 1 | 1,445 | 1,582 | 0.21% | 627 | 2.31 | CDP |
| Craig | 2 | 1,043 | 1,037 | 0.1% | 156 | 6.69 | City |
| Klawock | 3 | 705 | 717 | -0.28% | 1,035 | 0.68 | City |
| Kake | 4 | 533 | 542 | -0.37% | 69 | 7.67 | City |
| Thorne Bay | 5 | 466 | 475 | -0.43% | 17 | 26.67 | City |
| Hydaburg | 6 | 372 | 379 | -0.27% | 1,274 | 0.29 | City |
| Hollis | 7 | 144 | 198 | 1.41% | 2 | 65.06 | CDP |
| Coffman Cove | 8 | 124 | 126 | 0% | 11 | 10.90 | City |
| Naukati Bay | 9 | 122 | 110 | 0.83% | 25 | 4.79 | CDP |
| Whale Pass | 10 | 85 | 87 | 0% | 4 | 19.86 | City |
| Port Alexander | 11 | 72 | 74 | 0% | 21 | 3.50 | City |
| Kasaan | 12 | 30 | 30 | 0% | 5 | 6.06 | City |
| Edna Bay | 13 | 25 | 25 | 0% | 1 | 21.14 | City |
| Hyder | 14 | 20 | 12 | 5.26% | 1 | 17.14 | CDP |
Metlakatla is the largest city in Prince of Wales-Hyder Census Area, with a population of 1,445.
Hyder is the smallest city in Prince of Wales-Hyder Census Area.
There are 14 cities in Prince of Wales-Hyder Census Area, Alaska.