18 cities
| City | County | 2025 Pop. ↓ |
|---|---|---|
| East Ridge | Catoosa County | 21,809 |
| Elizabethton | Carter County | 14,150 |
| Erwin | Unicoi County | 5,939 |
| Eagleton Village | Blount County | 5,397 |
| Etowah | McMinn County | 3,748 |
| East Cleveland | Bradley County | 2,281 |
| Estill Springs | Franklin County | 2,272 |
| Englewood | McMinn County | 1,602 |
| Embreeville | Unicoi County | 1,248 |
| Erin | Houston County | 1,165 |
| Eagleville | Rutherford County | 1,020 |
| Eastview | McNairy County | 783 |
| Ethridge | Lawrence County | 573 |
| Elkton | Giles County | 527 |
| Enville | Chester County | 186 |
| Elgin | Scott County | 126 |
| Essary Springs | Hardeman County | 91 |
| Eva | Benton County | 48 |