
Isola
- County:
- Humphreys County
- County Seat:
- No
- Area (mi²):
- 0.739
- State:
- Mississippi
Isola is a town located in Humphreys County, Mississippi. Isola has a 2025 population of 562. Isola is currently declining at a rate of -2.43% annually and its population has decreased by -11.08% since the most recent census, which recorded a population of 632 in 2020.
The average household income in Isola is $117,394 with a poverty rate of 31.87%. The median age in Isola is 36.7 years: 36.4 years for males, and 39.5 years for females.