31 cities
| City | Rank | County | 2025 Pop. ↓ |
|---|---|---|---|
| Lamar | 1 | Prowers County | 7,409 |
| La Junta | 2 | Otero County | 6,845 |
| Rocky Ford | 3 | Otero County | 3,786 |
| Las Animas | 4 | Bent County | 2,424 |
| Springfield | 5 | Baca County | 1,269 |
| Fowler | 6 | Otero County | 1,181 |
| Ordway | 7 | Crowley County | 1,086 |
| Holly | 8 | Prowers County | 808 |
| Eads | 9 | Kiowa County | 607 |
| Swink | 10 | Otero County | 581 |
| Walsh | 11 | Baca County | 494 |
| North La Junta | 12 | Bent County | 448 |
| Granada | 13 | Prowers County | 432 |
| Wiley | 14 | Prowers County | 425 |
| Manzanola | 15 | Otero County | 324 |
| Olney Springs | 16 | Crowley County | 285 |
| Sugar City | 17 | Crowley County | 238 |
| Cheraw | 18 | Otero County | 229 |
| Crowley | 19 | Crowley County | 153 |
| La Junta Gardens | 20 | Bent County | 127 |
| McClave | 21 | Bent County | 116 |
| Pritchett | 22 | Baca County | 104 |
| Campo | 23 | Baca County | 93 |
| Vilas | 24 | Baca County | 90 |
| Hasty | 25 | Bent County | 79 |
| Haswell | 26 | Kiowa County | 69 |
| Sheridan Lake | 27 | Kiowa County | 54 |
| Hartman | 28 | Prowers County | 52 |
| Brandon | 29 | Kiowa County | 34 |
| Two Buttes | 30 | Baca County | 30 |
| Towner | 31 | Kiowa County | 13 |
Otero County, Prowers County, Bent County, Crowley County, Baca County, and Kiowa County are the counties generally considered part of Southeast Colorado.